Everything about The Bacteriophage Ms2 totally explained
The
bacteriophage MS2 or
Bacillus phage M2 (
Leviviridae) infects
Bacillus subtilis. MS2 phage is an icosahedral bacteriophage with a diameter of 27-34nm and an isoelectric point (pI) of 3.9. MS2 phage can be propagated in
Escherichia Coli, commonly
E. Coli ATCC 15597.
Genetics
This
phage has a very small genome which is 3,569 nucleotides long. In
1976 the complete
RNA sequence of Bacteriophage MS2 was determined, compared to the
DNA sequence of the
Phi-X174 phage, which was determined by
Fred Sanger and his team in
1977. These two genomes were the first to be determined in scientific history.
In
1962 it was established that the RNA of the phage was in a ring-structure. In
1972 a gene of Bacteriophage M2 was the first gene of which the nucleotide sequence was known. In
1976, it was the first organism (
virus) of which the complete genome was sequenced, by
Walter Fiers and his team at the
University of Ghent (
Ghent,
Belgium).
Further Information
Get more info on 'Bacteriophage Ms2'.
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